Cancer genomics, circulating biomarkers, exosomes, drug discovery & development, precision medicine, targeted therapies, tumor immunology, tumor microenvironment, bioinformatics, next generation sequencing, NGS data analysis on the cloud, GWAS & population genetics, SNP genotyping, multi-OMICs data interpretation, Bio-IT product development, oncology clinical research, scientific writing and teaching.
I am a physician scientist with medical degree from India and PhD in Biochemistry & Molecular Biology from University of North Dakota, Grand Forks, ND, USA. I have completed four years of post doctoral fellowship training from the prestigious MD Anderson Cancer Center, Houston, TX, USA. I have been actively involved in investigating tumor immunology, tumor microenvironment, developing novel targeted immuno-therapeutics and understanding tumor biology from a computational biology perspective. Currently I am working in cancer genomics field and exploring the SNPs (single nucleotide polymorphisms), INDELS (insertions and deletions), chromosomal rearrangements, gene fusion events and other mutations associated with heterogeneous tumors such as lung, breast and ovarian cancer. Recently, I have started exploring circulating tumor cells and circulating tumor DNA in the hopes of developing a commercially viable, technically sound and clinically valid reliable liquid biopsy assay for monitoring tumor recurrence and acquired resistance to targeted therapies.